Clinical Reactions and Tolerance to LSD in Chronic Schizophrenia

Clinical Reactions and Tolerance to LSD in Chronic Schizophrenia

Source: The Journal of Nervous and Mental Disease Vol 122 No 3 September 1955
Author(s): Louis S. Cholden MD, Albert Kurkland MD, Charles Savage MD

Back in 1955, LSD was still a new wunderkind that left those who worked with it both excited but baffled. In this short article, the authors outline the history of clinical LSD use up till that point until discussing the differences between chronic and deteriorated schizophrenia using an experimental group of twenty participants.
The authors’ main focus stays with stays with chronic schizophrenia and whether or not LSD can help as a therapeutic agent in such cases.
They also marked these studies with LSD against those done with mescaline, finding that “behavioral differences [are] not pronounced.”

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